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Immunogen sequence: MAKHLKFIA RTVMVQEGNV ESAYRTLNRI LTMDGLIEDI KHRRYYEKPC RRRQRESYER CRRIYNMEMA RKINFLMRKN RADPWQGC (1-87 aa encoded by BC004566)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein.
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蛋白别名: 28S ribosomal protein S21, mitochondrial; mitochondrial 28S ribosomal protein S21; MRP-S21; S21mt; Small ribosomal subunit protein bS21m
基因别名: 1810031B19Rik; MDS016; MRP-S21; MRPS21; RPMS21
UniProt ID: (Human) P82921, (Mouse) P58059
Entrez Gene ID: (Human) 54460, (Mouse) 66292, (Rat) 689432
分子生物学功能:
ribosomal protein