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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4.
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蛋白别名: 28S ribosomal protein S25, mitochondrial; mitochondrial 28S ribosomal protein S25; MRP-S25; rt25; S25mt; Small ribosomal subunit protein mS25
基因别名: 2810429N01Rik; MRP-S25; MRPS25; RPMS25; Shd10
UniProt ID: (Human) P82663, (Mouse) Q9D125, (Rat) Q4QR80
Entrez Gene ID: (Human) 64432, (Mouse) 64658, (Rat) 297459