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Immunogen sequence: MSRQSTLYS FFPKSPALSD ANKASARASR EGGRAAAAPG ASPSPGGDAA WSEAGPGPRP LARSASPPKA KNLNGGLRRS VAPAAPTSCD FSPGDLVWAK MEGYPWWPCL VYNHPFDGTF IREKGKSVRV HVQFFDDSPT RGWVSKRLLK PYTGSKSKEA QKGGHFYSAK PEILRAMQRA DEALNKDKIK RLELAVCDEP SEPEEEEEME VGTTYVTDKS EEDNEIESEE EVQPKTQGSR RSSRQIKKRR VISDSESDIG GSDVEFKPDT KEEGSSDEIS SGVGDSESEG LNSPVKVARK RKRMVTGNGS LKRKSSRKET PSATKQATSI SSETKNTLRA FSAPQNSESQ AHVSGGGDDS SRPTVWYHET LEWLKEEKRR DEHRRRPDHP DFDASTLYVP E (1-400 aa encoded by BC004246)
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; hMSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS protein homolog 6; MutS-alpha 160 kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein; sperm-associated protein
基因别名: AU044881; AW550279; GTBP; GTMBP; HNPCC5; HSAP; MSH6; p160
UniProt ID: (Human) P52701, (Mouse) P54276
Entrez Gene ID: (Human) 2956, (Mouse) 17688