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Positive test controls include: 293T, PC-3, Mouse heart, Mouse brain.
Immunogen sequence: MNFALILMIN TLLALLLMII TFWLPQLNGY MEKSTPYECG FDPMSPARVP FSMKFFLVAI TFLLFDLEIA
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1.6.5.3; NADH dehydrogenase subunit 3; NADH-ubiquinone oxidoreductase chain 3
基因别名: MT-ND3; MTND3; NADH3; ND3
UniProt ID: (Rat) P05506, (Mouse) P03899
Entrez Gene ID: (Rat) 26199, (Mouse) 17718