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This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5'-methylthioadenosine phosphorylase; epididymis luminal protein 249; MeSAdo phosphorylase; MTA phosphorylase; MTAP; MTAPase; S-methyl-5'-thioadenosine phosphorylase
基因别名: 1300019I21Rik; BDMF; c86fus; Cc1-6; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP; MTAP
UniProt ID: (Human) Q13126, (Mouse) Q9CQ65
Entrez Gene ID: (Human) 4507, (Mouse) 66902, (Rat) 298227