Bioss

MTGR1 Polyclonal Antibody

产品信息

BS-8304R

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:100-1:500

免疫组化（冰冻） (IHC (F))

1:100-1:500

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1:500-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human MTGR1, amino acids 321-420.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CBFA2T2 identified gene homolog; core-binding factor runt domain alpha subunit 2 translocated to 2 homolog; core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog; core-binding factor, runt domain, alpha subunit 2; translocated to, 2; DKFZp313F2116; ETO homolog on chromosome 20; ETO homologous on chromosome 20; MTG8-like protein; MTG8-related protein 1; myeloid translocation gene-related protein 1; Myeloid translocation-related protein 1; p85; Protein CBFA2T2; RP5-1137F22.1; translocated to, 2; ZMYND3 CBFA2T2

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基因别名: A430091M07; C330013D05Rik; CBFA2T2; Cbfa2t2h; EHT; MTGR1; p85; ZMYND3

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UniProt ID: (Human) O43439, (Mouse) O70374

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Entrez Gene ID: (Human) 9139, (Rat) 296293, (Mouse) 12396

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功能

transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding metal ion binding transcription cofactor

参与通路

transcription, DNA-templated positive regulation of neuron projection development negative regulation of neuron projection development epithelial cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated negative regulation of nucleic acid-templated transcription