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Recommended positive controls: 293T.
Predicted reactivity: Mouse (89%), Zebrafish (80%), Xenopus laevis (81%), Chicken (85%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5,10-methylenetetrahydrofolate reductase (NADPH); Methylenetetrahydrofolate reductase (NADPH); RP11-56N19.4
基因别名: MTHFR
UniProt ID: (Human) P42898
Entrez Gene ID: (Human) 4524
分子生物学功能:
reductase