Invitrogen

MVK Polyclonal Antibody

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MVK Antibody (PA5-119727) in WB

Western blot analysis of MVK on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. MVK Polyclonal Antibody (Product # PA5-119727) at 1:500 was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: U937 cell lysate. Lane 2: SKBR-3 cell lysate.

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产品信息

PA5-119727

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500

流式细胞分析 (Flow)

1:50-1:100

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein within human MVK aa 200-396

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

TBS, pH 7.4, with 50% glycerol, 0.2% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2913300

产品详细信息

Positive Control: U937 cell lysate, SKBR-3 cell lysate, HepG2.

Subcellular Location: Cytoplasm, Peroxisome.

靶标信息

Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Deficiency in MVK activity contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).

仅用于科研。不用于诊断过程。未经明确授权不得转售。