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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MELNSLLILL EAAEYLERRD REAEHGYASV LPFDGDFARE KTKAAGLVRK APNNRSSHNE LEKHRRAKLR LYLEQLKQLV PLGPDSTRHT TLSLLKRAKV HIKKLEEQDR RALSIKEQLQ QEHRFLKRRL EQLSVQSVER VRTDSTGSAV STDDSEQEVD IEGMEFGPGE LDSVGSSSDA DDHYSLQSGT GGDSGFGPHC RRLGRPALS
This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHc12; Class C basic helix-loop-helix protein 12; Mad4 homolog; Max dimerization protein 4; Max dimerizer 4; Max-associated protein 4; Max-interacting transcriptional repressor MAD4
基因别名: BHLHC12; MAD4; MST149; MSTP149; MXD4
UniProt ID: (Human) Q14582
Entrez Gene ID: (Human) 10608