Proteintech

MYBBP1A Polyclonal Antibody

MYBBP1A Antibody in Immunocytochemistry (ICC/IF)

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MYBBP1A Antibody (14524-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using MYBBP1A antibody 14524-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

MYBBP1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MYBBP1A Antibody in Flow Cytometry (Flow)

MYBBP1A Antibody in Immunoprecipitation (IP)

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产品信息

14524-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫细胞化学 (ICC/IF)

1:20-1:200

查看1篇已发表文章 1篇已发表文章

流式细胞分析 (Flow)

0.2 µg/1x10^6 cells

免疫沉淀 (IP)

0.5-4.0 µg

产品规格

种属反应

Human

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

MYBBP1A Fusion Protein Ag6008 (979-1328 aa encoded by BC050546)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.35 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: STALSSFLT KRNSPLTVPM FLSLFSRHPV LCQSLLPILV QHITGPVRPR RQACLLLQKT LSMREVRSCF EDPEWKQLMG QVLAKVTENL RVLGEAQTKA QHQQALSSLE LLNVLFRTCK HEKLTLDLTV LLGVLQGQQQ SLQQGAHSTG SSRLHDLYWQ AMKTLGVQRP KLEKKDAKEI PSATQSPISK KRKKKGFLPE TKKRKKRKSE DGTPAEDGTP AATGGSQPPS MGRKKRNRTK AKVPAQANGT PTTKSPAPGA PTRSPSTPAK SPKLQKKNQK PSQVNGAPGS PTEPAGQKQH QKALPKKGVL GKSPLSALAR KKARLSLVIR SPSLLQSGAK KKAQVRKAGK P (979-1328 aa encoded by BC050546)

靶标信息

The Myb family of transcription factors, which includes the structurally related A-, B-, and c-Myb genes, regulate differentiation, cellular growth and transactivating gene expression. c-Myb plays an essential role in controlling the proliferation and differentiation of hematopoietic cells, cellular levels of c-Myb decreasing as cells reach terminal differentiation. Myb-binding protein 1A (MYBBP1A) is a novel nuclear protein localized predominantly, but not exclusively, in nucleoli. Although initially isolated as a c-Myb-interacting protein, MYBBP1A is expressed ubiquitously, and associates with a number of different transcription factors. MYBBP1A associates with the aromatic hydrocarbon receptor (AhR), enhancing transactivation and increasing AhR-dependent gene expression. MYBBP1A is a powerful negative regulator of PPAR gamma coactivator 1 alpha (PGC-1 alpha) by p38 MAPK and also acts as a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways.

仅用于科研。不用于诊断过程。未经明确授权不得转售。