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Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MLC-2a; MLC2a; myosin light chain 2a; myosin light chain, regulatory A; Myosin regulatory light chain 2, atrial isoform; Myosin regulatory light chain 7; myosin, light chain 7, regulatory; myosin, light polypeptide 7, regulatory
基因别名: MLC-2alpha; MLC2a; MYL2A; MYL7; MYLC2A; RLC-A
UniProt ID: (Human) Q01449, (Mouse) Q9QVP4
Entrez Gene ID: (Human) 58498, (Rat) 289759, (Mouse) 17898