Search Thermo Fisher Scientific
图: 1 / 8
Keep as concentrated solution.
Predicted reactivity: Mouse (97%), Rat (97%), Bovine (92%).
Positive Control: U87-MG, SK-N-SH nuclear, IMR32 nuclear extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Myelin transcription factor 1; Myelin transcription factor I; MyT1; MyTI; Neural zinc finger factor 2; neural zinc finger transcription factor 2; NZF-2; PLPB1; proteolipid protein binding protein; Proteolipid protein-binding protein
基因别名: C20orf36; KIAA0835; KIAA1050; MTF1; MYT1; MYTI; NZF2; Nzf2a; Nzf2b; Nztf2; PLPB1; ZC2H2C1; ZC2HC4A
UniProt ID: (Human) Q01538, (Mouse) Q8CFC2
Entrez Gene ID: (Human) 4661, (Mouse) 17932