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MZB1 Antibody (PA5-21794) in IHC (P)
PACAP Polyclonal Antibody detects PACAP protein at cytosol on human normal colon mucosa with lymphocyte by immunohistochemical analysis. Sample: Paraffin-embedded normal colon mucosa with lymphocyte. PACAP Polyclonal Antibody (Product # PA5-21794) dilution: 1:500.
产品信息
PA5-21794
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 189 of PACAP (Uniprot ID#Q8WU39)
偶联物
形式
Liquid
浓度
0.48 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152981
产品详细信息
Recommended positive controls: Molt-4, Raji.
Predicted reactivity: Rhesus Monkey (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caspase-2 binding protein; HSPC190; marginal zone B and B1 cell-specific protein; Marginal zone B- and B1-cell-specific protein; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
基因别名: 2010001M09Rik; AV064572; HSPC190; MEDA-7; MEDA7; MZB1; PACAP; pERp1
UniProt ID: (Human) Q8WU39, (Mouse) Q9D8I1
Entrez Gene ID: (Human) 51237, (Mouse) 69816
