Invitrogen

Metallothionein Monoclonal Antibody (UC1MT)

Metallothionein Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Metallothionein Antibody (MA1-25479) in IHC (P)

Immunohistochemistry (Paraffin) analysis of Metallothionein in human uterus tissue using Metallothionein Monoclonal Antibody (UC1MT) (Product # MA1-25479) at a dilution of 10 µg/mL.

Metallothionein Antibody in Western Blot (WB)

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产品信息

MA1-25479

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

Assay-dependent

酶联免疫吸附实验 (ELISA)

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产品规格

种属反应

Horse, Fish, Human, Mouse, Rabbit, Rat

已发表种属

Human, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

UC1MT

抗原

Full length protein from cross linked rabbit liver MT1 and MT2.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_794848

产品详细信息

A band of approximately 15 kDa is detected.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Single-cell sequencing reveals microglia induced angiogenesis by specific subsets of endothelial cells following spinal cord injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yao C,Cao Y,Wang D,Lv Y,Liu Y,Gu X,Wang Y,Wang X,Yu B

MA1-25479 was used in Immunohistochemistry (Paraffin), Western Blot to indicate that immune cells promote angiogenesis by regulating specific subsets of vascular endothelial cells (ECs), which provides new clues for exploring Spinal cord injury (SCI) intervention.

Fri Jul 01 00:00:00 EDT 2022

Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Wistar Rat Testis.

Cells

Migliaccio V,Sica R,Scudiero R,Simoniello P,Putti R,Lionetti L

MA1-25479 was used in Western Blotting to evaluate the adaptive responses in testis of adult rats treated with a non-toxic dose of dichlorodiphenyldichloroethylene alone or in association with a high-fat diet.