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Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mimecan; Osteoglycin
基因别名: 3110079A16Rik; mimecan; mimican; OG; Ogn; OIF; SLRR3A
UniProt ID: (Mouse) Q62000
Entrez Gene ID: (Mouse) 18295