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产品信息
MA5-44192
应用
建议稀释比
已发表文章
产品规格
种属反应
Tag
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
BLRE01G
抗原
Peptide representing amino acid residues 410-419 (EQKLISEEDL) of human myc
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
purified
保存液
BBS, pH 7.8-8.6, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
2-8°C
运输条件
Wet ice
RRID
AB_2926322
产品详细信息
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
靶标信息
Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 46-0603; c Myc; c-myc epitope tag; cmyc; Myc Tag; R950-25; R95025
