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Invitrogen
Myeloperoxidase Polyclonal Antibody
高级验证
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
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Myeloperoxidase Antibody (DOM00001G) in WB
Western blot was performed using Anti-Myeloperoxidase Rabbit Polyclonal Antibody (Product # DOM00001G) and 87 kDa, 73 kDa, 60 kDa and 15 kDa bands corresponding to MPO was observed across cell lines except K-562 and A-431, also it was observed to decrease upon Retinoic Acid treatment. Membrane enriched extracts (30 µg lysate) of HL-60 (Lane 1), HL-60 treated with Retinoic Acid (1uM for 72 Hours) (Lane 2), K-562 (Lane 3) and A-431 (Lane 4) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins... View More
产品信息
DOM00001G
应用
建议稀释比
已发表文章
产品规格
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Native myeloperoxidase isolated from human leucocytes
偶联物
形式
Lyophilized
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_962160
产品详细信息
Glycerol (1:1) may be added for additional stability.
Reconstitute with 500 µL of distilled water.
Centrifuge to remove any insoluble material.
靶标信息
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
