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Immunogen sequence: SEVLLVSEDG KILAEADGLS TNHWLIGTDK CVERINEMVN RAKRKAGVDP LVPLRSLGLS LSGGDQEDAG RILIEELRDR FPYLSE
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GlcNAc kinase; Muramyl dipeptide kinase; N-acetyl-D-glucosamine kinase; N-acetyl-D-mannosamine kinase; N-acetylglucosamine kinase
基因别名: GNK; HSA242910; NAGK
UniProt ID: (Human) Q9UJ70
Entrez Gene ID: (Human) 55577