Invitrogen

NAPSA Monoclonal Antibody (A9B12)

NAPSA Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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NAPSA Antibody (MA5-50614) in IHC (P)

Immunohistochemistry of NAPSA in paraffin-embedded human lung carcinoma tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with NAPSA monoclonal antibody (Product # MA5-50614) with a dilution of 1:1,000 for 1 hour at room temp... View More

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产品信息

MA5-50614

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

A9B12

抗原

Recombinant protein within human NAPSIN A aa 51-200/420.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_3091206

产品详细信息

Positive control: Human kidney tissue, human lung carcinoma tissue.

Predicted band size: 45 kDa

Subcellular Location: Secreted.

靶标信息

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.

仅用于科研。不用于诊断过程。未经明确授权不得转售。