Search Thermo Fisher Scientific
图: 1 / 4
Positive Samples: Mouse brain, Rat brain; Cellular Location: Golgi apparatus membrane
Immunogen sequence: MTEVVPSSAL SEVSLRLLCH DDIDTVKHLC GDWFPIEYPD SWYRDITSNK KFFSLAATYR GAIVGMIVAE IKNRTKIHKE DGDILASNFS VDTQVAYILS LGVVKEFRKH GIGSLLLESL KDHISTTAQD HCKAIYLHVL TTNNTAINFY ENRDFKQHHY LPYYYSIRGV LKDGFTYVLY INGG
Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GNAT acetyltransferase; GNAT acetytransferase; HAT4; Histone acetyltransferase type B protein 4; hNaa60; N-acetyltransferase 15; N-acetyltransferase 15 (GCN5-related, putative); N-alpha-acetyltransferase 60; N-alpha-acetyltransferase F; NatF; natF catalytic subunit
基因别名: 1200013P24Rik; AI315146; HAT4; NAA60; NAT15; RGD1308915; UNQ2771/PRO7155
UniProt ID: (Human) Q9H7X0, (Mouse) Q9DBU2, (Rat) Q3MHC1
Entrez Gene ID: (Human) 79903, (Mouse) 74763, (Rat) 363545
分子生物学功能:
acetyltransferase