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Immunogen sequence: PEYEGIWADL QELWFLGMQA FTGCVPLLPW LAPAALRSRW PQELLQLLGS VSPNSVKPEM VAAYQGVLVE LARANRLCRE AMRLQAGEET ASHYRMAA
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: M-Sema F-associating protein of 75 kDa; minisatellite 10ae detected by probe MMS10; Neurite outgrowth-related protein from the rat brain; Neurochondrin; neurochondrin-1; neurochondrin-2; Norbin
基因别名: AU042419; KIAA0607; mKIAA0607; MMS10-AE; Ms10ae; NCDN; Norbin; Sfap75
UniProt ID: (Human) Q9UBB6, (Mouse) Q80TW1, (Rat) O35095
Entrez Gene ID: (Human) 23154, (Mouse) 26562, (Rat) 89791