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产品信息
PA5-87297
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human NDE1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2804044
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
NDE1 is s a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations to the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
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生物信息学
蛋白别名: LIS1-interacting protein NUDE1, rat homolog; Nuclear distribution protein nudE homolog 1; NudE; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1
基因别名: 2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS4; MHAC; mNudE; NDE; NDE1; NUDE; NUDE1
UniProt ID: (Human) Q9NXR1, (Mouse) Q9CZA6
Entrez Gene ID: (Human) 54820, (Mouse) 67203
establishment of mitotic spindle orientation
neuron migration
microtubule nucleation
cell cycle
chromosome segregation
mitotic nuclear division
mitotic centrosome separation
multicellular organism development
nervous system development
neuroblast proliferation
cerebral cortex development
cell differentiation
forebrain development
microtubule organizing center organization
vesicle transport along microtubule
centrosome duplication
cell division
establishment of chromosome localization
centrosome localization
G2/M transition of mitotic cell cycle
sister chromatid cohesion
cell migration
regulation of microtubule motor activity
