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产品信息
18940-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NECAB3 Fusion Protein Ag13493 (1-362 aa encoded by BC047673)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MACAGLLTV CLLRPPAPQP QPQTPRHPQL APDPGPAGHT LFQDVFRRAD KNDDGKLSFE EFQNYFADGV LSLGELQELF SGIDGHLTDN LETEKLCDYF SEHLGVYRPV LAALESLNRA VLAAMDATKL EYERASKVDQ FVTRFLLRET VSQLQALQSS LEGASDTLEA QAHGWRSDAE SVEAQSRLCG SRRAGRRALR SVSRSSTWSP GSSDTGRSSE AEMQWRLQVN RLQELIDQLE CKAPRLEPLR EEDLAKGPDL HILMAQRQVQ VAEEGLQDFH RALRCYVDFT GAQSHCLHVS AQKMLDGASF TLYEFWQDEA SWRRHQQSPG SKAFQRILID HLRAPDTLTT VFFPASWWIM NNN (1-362 aa encoded by BC047673)
靶标信息
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: amyloid beta (A4) precursor protein-binding family A member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein; amyloid beta A4 protein-binding family A member 2-binding protein; Amyloid-beta A4 protein-binding family A member 2-binding protein; EF-hand calcium binding protein 3; mXB51; N-terminal EF-hand calcium-binding protein 3; Nek2-interacting protein 1; Neuronal calcium-binding protein 3; neuronal calcium-binding protein NECAB3; synaptotagmin interacting protein 2; synaptotagmin interacting protein STIP3; X11L-binding protein 51
基因别名: 2900010M17Rik; AI853434; APBA2BP; dJ63M2.4; dJ63M2.5; EFCBP3; NECAB3; NIP1; STIP3; SYTIP2; XB51
UniProt ID: (Human) Q9HBW7, (Mouse) Q9D6J4
Entrez Gene ID: (Human) 63941, (Mouse) 56846, (Rat) 311562
