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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSQTSGGEAG SPPPAVVAAD ASSAPSSSSM GGACSSFTTS SSPTIYSTSV TDSKAMQVES CSSAVGVSNR GVSEKQLTSN TVQQHPSTPK RHTVLYISPP PEDLLDNSRM SCQDEGCGLE SEQSCSMWME DSPSNFSNMS TSSYNDNTEV PRKSRKRNPK QRPGVKRRDC EESNMDIFDA DSAKAPHYVL SQLTTDNKGN SKAGNGTLEN QKGTGVKKSP MLCGQYPVKS EGKELKIVVQ PETQHRARYL TEGSRGSVKD RTQQGFPTVK LEGHNEPVVL QVFVGNDSGR VKPHGFYQAC RVTGRNTTPC KEVDIEGTTV IEVGLDPSNN MTLAVDCVGI LKLRNADVEA RIGIAGSKKK STRARLVFRV NIMRKDGSTL TLQTPSSPIL CTQPAGVPEI LKKSLHSCSV KGEEEVFLIG KNFLKGTKVI FQENVSDENS WKSEAEIDME LFHQNHLIVK VPPYHDQHIT LPVSVGIYVV TNAGRSHDVQ PFTYTPDPAA AGALNVNVKK EISSPARPCS FEEAMKAMKT TGCNLDKVNI IPNALMTPLI PSSMIKSEDV TPMEVTAEKR SSTIFKTTKS VGSTQQTLEN ISNIAGNGSF SSPSSSHLPS ENEKQQQIQP KAYNPETLTT IQTQDISQPG TFPAVSASSQ LPNSDALLQQ ATQFQTRETQ SREILQSDGT VVNLSQLTEA SQQQQQSPLQ EQAQTLQQQI SSNIFPSPNS VSQLQNTIQQ LQAGSFTGST ASGSSGSVDL VQQVLEAQQQ LSSVLFSAPD GNENVQEQLS ADIFQQVSQI QSGVSPGMFS STEPTVHTRP DNLLPGRAES VHPQSENTLS NQQQQQQQQQ QVMESSAAMV MEMQQSICQA AAQIQSELFP STASANGNLQ QSPVYQQTSH MMSALSTNED MQMQCELFSS PPAVSGNETS TTTTQQVATP GTTMFQTSSS GDGEETGTQA KQIQNSVFQT MVQMQHSGDN QPQVNLFSST KSMMSVQNSG TQQQGNGLFQ QGNEMMSLQS GNFLQQSSHS QAQLFHPQNP IADAQNLSQE TQGSLFHSPN PIVHSQTSTT SSEQMQPPMF HSQSTIAVLQ GSSVPQDQQS TNIFLSQSPM NNLQTNTVAQ EAFFAAPNSI SPLQSTSNSE QQAAFQQQAP ISHIQTPMLS QEQAQPPQQG LFQPQVALGS LPPNPMPQSQ QGTMFQSQHS IVAMQSNSPS QEQQQQQQQQ QQQQQQQQQS ILFSNQNTMA TMASPKQPPP NMIFNPNQNP MANQEQQNQS IFHQQSNMAP MNQEQQPMQF QSQSTVSSLQ NPGPTQSESS QTPLFHSSPQ IQLVQGSPSS QEQQVTLFLS PASMSALQTS INQQDMQQSP LYSPQNNMPG IQGATSSPQP QATLFHNTAG GTMNQLQNSP GSSQQTSGMF LFGIQNNCSQ LLTSGPATLP DQLMAISQPG QPQNEGQPPV TTLLSQQMPE NSPLASSINT NQNIEKIDLL VSLQNQGNNL TGSF
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: glutamine rich protein H65; NF-AT5; NFAT-like protein 1; Nuclear factor of activated T-cells 5; osmotic response element-binding protein; T-cell transcription factor NFAT5; TonE-binding protein; Tonicity-responsive enhancer-binding protein
基因别名: KIAA0827; NF-AT5; NFAT5; NFATL1; NFATZ; OREBP; TONEBP
UniProt ID: (Human) O94916
Entrez Gene ID: (Human) 10725