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产品信息
PA5-116955
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 21-198 of human Lipocalin-2/NGAL (NP_0055552)
偶联物
形式
Liquid
浓度
1.64 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901585
产品详细信息
Positive Samples: DU145, HT-29, BxPC-3, Mouse spleen
Immunogen sequence: QDSTSDLIPA PPLSKVPLQQ NFQDNQFQGK WYVVGLAGNA ILREDKDPQK MYATIYELKE DKSYNVTSVL FRKKKCDYWI RTFVPGCQPG EFTLGNIKSY PGLTSYLVRV VSTNYNQHAM VFFKKVSQNR EYFKITLYGR TKELTSELKE NFIRFSKSLG LPENHIVFPV PIDQCIDG
靶标信息
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
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生物信息学
蛋白别名: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HGNC:6526; Lipocalin-2; Lipocalin2; migration-stimulating factor inhibitor; Neutrophil gelatinase-associated lipocalin; NGAL; Oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; SV-40-induced 24P3 protein; uterocalin
基因别名: 24p3; AW212229; HNL; LCN2; MSFI; NGAL; p25; Sip24
UniProt ID: (Human) P80188, (Mouse) P11672
Entrez Gene ID: (Human) 3934, (Mouse) 16819
ion transport
cellular iron ion homeostasis
apoptotic process
siderophore transport
innate immune response
immune system process
transport
response to virus
response to herbicide
positive regulation of gene expression
positive regulation of cell projection organization
response to drug
iron ion homeostasis
protein homotrimerization
cellular response to hydrogen peroxide
extrinsic apoptotic signaling pathway in absence of ligand
