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NGAL Antibody (PA5-79591) in IHC (P)
Immunohistochemistry analysis of NGAL on paraffin-embedded mouse spleen tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with NGAL polyclonal antibody (Product# PA5-79591) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). Developme... View More
产品信息
PA5-79591
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived rat Lipocalin 2 recombinant protein (Position: Q21-N198).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746706
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; HGNC:6526; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin-2; Lipocalin2; migration-stimulating factor inhibitor; Neutrophil gelatinase-associated lipocalin; NGAL; Oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; SV-40-induced 24P3 protein; uterocalin
基因别名: 24p3; AW212229; HNL; LCN2; MSFI; NGAL; p25; Sip24
UniProt ID: (Human) P80188, (Mouse) P11672, (Rat) P30152
Entrez Gene ID: (Human) 3934, (Mouse) 16819, (Rat) 170496
ion transport
cellular iron ion homeostasis
apoptotic process
siderophore transport
innate immune response
immune system process
transport
response to virus
response to herbicide
positive regulation of gene expression
positive regulation of cell projection organization
response to drug
iron ion homeostasis
protein homotrimerization
cellular response to hydrogen peroxide
extrinsic apoptotic signaling pathway in absence of ligand
response to oxidative stress
response to bacterium
response to mycotoxin
response to nutrient levels
cellular response to nutrient levels
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
