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产品信息
PA5-112910
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human N-myc-interactor protein (62-202AA)
偶联物
形式
Liquid
浓度
7 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2867644
靶标信息
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: N-myc (and STAT) interactor; N-myc and STAT interactor; N-myc interactor; N-myc-interactor; Nmi
基因别名: NMI
UniProt ID: (Human) Q13287
Entrez Gene ID: (Human) 9111, (Rat) 311021
transcription from RNA polymerase II promoter
inflammatory response
JAK-STAT cascade
negative regulation of interferon-alpha biosynthetic process
negative regulation of interferon-beta biosynthetic process
negative regulation of innate immune response
interferon-gamma-mediated signaling pathway
positive regulation of protein K48-linked ubiquitination
regulation of nucleic acid-templated transcription
biological_process
