Invitrogen

NPHP3 Polyclonal Antibody

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NPHP3 Antibody (PA5-97123) in WB

Western blot analysis of NPHP3 in extracts of various cell lines. Samples were incubated with NPHP3 Polyclonal antibody (Product # PA5-97123) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

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产品信息

PA5-97123

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200-1:2,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human NPHP3 (NP_6949723)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.54 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2808925

产品详细信息

Immunogen sequence: MGTASSLVSP AGGEVIEDTY GAGGGEACEI PVEVKPKARL LRNSFRRGAG AAAGAGPGSL PRGVGAGGLL GASFKSTGSS VPELEYAAAE YERLRKEYEI FRVSKNQELL SMGRREAKLD TENKRLRAEL; Positive Samples: 293T, Mouse liver; Cellular Location: Cell projection, cilium

靶标信息

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

仅用于科研。不用于诊断过程。未经明确授权不得转售。