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Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Pig (100%).
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BD73; EAR-1; nuclear receptor protein; nuclear receptor Rev-ErbA-alpha; Nuclear receptor subfamily 1 group D member 1; nuclear receptor subfamily 1, group D, member 1; orphan nuclear receptor; rev-erb alpha; Rev-erba; rev-erbA alpha; rev-erbA(alpha); Rev-erbA-alpha; Rev-ErbA-alpha protein; Rev-ErbAalpha; REV-ERBalpha; Reverbaalpha; V-erbA-related protein 1; V-erbA-related protein EAR-1
基因别名: A530070C09Rik; ear-1; EAR1; HREV; I79_018778; NR1D1; R75201; REV-ERBAALPHA; THRA1; THRAL
UniProt ID: (Human) P20393, (Bovine) Q08E02, (Rat) Q63503, (Mouse) Q3UV55
Entrez Gene ID: (Horse) 100054466, (Human) 9572, (Pig) 641342, (Bovine) 768225, (Dog) 100688236, (Rabbit) 100357678, (Chinese hamster) 100771327, (Rat) 252917, (Mouse) 217166
分子生物学功能:
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator