Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-100648
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NR1D2(Accession Q14995), corresponding to amino acid residues M447-Q497.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2850153
产品详细信息
Antibody detects endogenous levels of total NR1D2.
靶标信息
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: EAR-1R; EAR4; HZF2; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2; Nuclear receptor subfamily 1 group D member 2; nuclear receptor subfamily 1, group D, member 2; Orphan nuclear hormone receptor BD73; orphan nuclear receptor HZF-2; Orphan nuclear receptor RVR; orphan receptor; Rev-erb alpha-related receptor; Rev-erb beta; Rev-erb-beta; Rev-erb-Beta2; Rev-erba beta; rev-erba-alpha-related receptor; Rev-ErbA-beta; Rev-erbabeta; RVR; V-erbA-related protein 1-related
基因别名: BD73; EAR-1R; HZF-2; NR1D2; Rev-erb; RVR
UniProt ID: (Human) Q14995, (Mouse) Q60674, (Rat) Q63504
Entrez Gene ID: (Human) 9975, (Mouse) 353187, (Rat) 259241
core promoter sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
DNA binding
transcription factor activity, sequence-specific DNA binding
thyroid hormone receptor activity
sequence-specific DNA binding
metal ion binding
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
regulation of lipid metabolic process
intracellular receptor signaling pathway
regulation of circadian rhythm
steroid hormone mediated signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
regulation of inflammatory response
lipid homeostasis
regulation of energy homeostasis
regulation of skeletal muscle cell differentiation
transcription, DNA-templated
