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产品信息
500-P83GBT-25UG
产品规格
种属反应
Human
宿主/亚型
Goat
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived, 28.1 kDa Recombinant Human NT-4
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
AB_2930801
产品详细信息
AA Sequence of recombinant protein: GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA.
Preparation: Produced from sera of goats immunized with highly pure Recombinant Human NT-4. Anti-Human NT-4-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect hNT-4 by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human NT-4 (500-P83G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hNT-4.
Western Blot: To detect hNT-4 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hNT-4 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P83GBT-1MG will be provided as 2 x 500 µg
靶标信息
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
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生物信息学
蛋白别名: neurotrophic factor 4; neurotrophic factor 5; Neurotrophin 4/5; neurotrophin 5 (neurotrophin 4/5); Neurotrophin-4; Neurotrophin-5; Neutrophic factor 4; Neutrophic factor 5; NT-4; NT-5; NT4/NT5
基因别名: GLC10; GLC1O; NT-4; NT-4/5; NT-5; NT4; NT5; NTF4; NTF5
UniProt ID: (Human) P34130
Entrez Gene ID: (Human) 4909
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
ganglion mother cell fate determination
long-term memory
sensory organ boundary specification
adult locomotory behavior
epidermis development
mechanoreceptor differentiation
negative regulation of neuron apoptotic process
regulation of neuron differentiation
neuron projection morphogenesis
innervation
taste bud development
