Invitrogen

NTN1 Polyclonal Antibody

NTN1 Antibody in Immunocytochemistry (ICC/IF)

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NTN1 Antibody (PA5-18446) in ICC/IF

Immunocytochemistry analysis of NTN1 using NTN1 Polyclonal Antibody (Product # PA5-18446) in paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing membrane and secreted staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).

NTN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-18446

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫细胞化学 (ICC/IF)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (KFQQREKKGKCKKA) corresponding to the C-terminus amino acids of NTN1 (aa 591-604).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_10985273

产品详细信息

This antibody is predicted to react with bovine and canine based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

靶标信息

Netrin-1 is a protein target that plays a crucial role in various biological processes, particularly in the development and guidance of neuronal cells. It belongs to the netrin family of axon guidance molecules and is involved in mediating axon guidance, cell migration, and tissue morphogenesis during embryonic development. Netrin-1 functions by binding to specific receptors on the cell surface and providing directional cues for cellular movement and connectivity. Dysregulation of Netrin-1 has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular conditions.

仅用于科研。不用于诊断过程。未经明确授权不得转售。