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产品信息
PA5-55369
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human NTS. Recombinant protein control fragment (Product #RP-88682).
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2644847
产品详细信息
Immunogen sequence: DFLTNMHTSK LIQEDILDTG NDKNGKEEVI KRKIPYILKR QLYENKPRRP
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 70%.
靶标信息
NTS is a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
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生物信息学
蛋白别名: Neurotensin/neuromedin N; NmN; pro-neurotensin/neuromedin
基因别名: NMN-125; NN; NT; NT/N; NTS; NTS1
UniProt ID: (Human) P30990
Entrez Gene ID: (Human) 4922
liver development
response to amphetamine
hyperosmotic response
signal transduction
visual learning
response to estradiol
response to cocaine
digestive tract development
response to axon injury
regulation of blood vessel size
response to corticosterone
cellular response to lithium ion
cellular response to dexamethasone stimulus
response to antipsychotic drug
cellular response to nerve growth factor stimulus
