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产品信息
PA5-51213
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full length fusion protein of human NUDT4
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636661
产品详细信息
The antibody detects endogenous levels of total NUDT4 protein.
靶标信息
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A. The major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; Diphosphoinositol polyphosphate phosphohydrolase 2; Diphosphoinositol polyphosphate phosphohydrolase NUDT4B; diphosphoinositol polyphosphate phosphohydrolase type 2; DIPP-2; DIPP-2B; Nucleoside diphosphate-linked moiety X motif 4; Nucleoside diphosphate-linked moiety X motif 4B; nudix (nucleoside diphosphate linked moiety X)-type motif 4; Nudix hydrolase 4B; Nudix motif 4; Nudix motif 4B
基因别名: DIPP2; DIPP2alpha; DIPP2beta; HDCMB47P; KIAA0487; NUDT4; NUDT4B
UniProt ID: (Human) A0A024RBG1
Entrez Gene ID: (Human) 11163
protein binding
diphosphoinositol-polyphosphate diphosphatase activity
snoRNA binding
metal ion binding
m7G(5')pppN diphosphatase activity
inositol diphosphate tetrakisphosphate diphosphatase activity
inositol bisdiphosphate tetrakisphosphate diphosphatase activity
inositol diphosphate pentakisphosphate diphosphatase activity
inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity
inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity
inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
phosphatase
