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NUDT6 Antibody (PA5-102309) in IHC (P)
Immunohistochemistry analysis of NUDT6 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with NUDT6 polyclonal antibody (Product # PA5-102309) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-102309
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NUDT6(Accession P53370), corresponding to amino acid residues V144-E194.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851718
产品详细信息
Antibody detects endogenous levels of total NUDT6.
靶标信息
NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6), also known as Antisense basic fibroblast growth factor or GFG-1, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. The gene encoding NUDT6 is a FGF-2 gene antisense transcript, and NUDT6 is believed to regulate FGF-2 expression. FGF-2 is a mutifunctional heparin-binding growth factor important to angiogenesis, neuroectoderm development and wound healing. NUDT6 is expressed as two isoforms produced by alternative splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: anti-sense basic fibroblast growth factor B; Antisense basic fibroblast growth factor; Antisense basic fibroblast growth factor B; Nucleoside diphosphate-linked moiety X motif 6; nudix (nucleoside diphosphate linked moiety X)-type motif 6; Nudix motif 6; Protein GFG
基因别名: ASFGF2; Asfgf2b; FGF-AS; FGF2AS; Gfg; GFG-1; GFG1; NUDT6
UniProt ID: (Human) P53370, (Rat) P70563, (Mouse) Q8CH40
Entrez Gene ID: (Human) 11162, (Rat) 207120, (Mouse) 229228
growth factor activity
hydrolase activity
thiamine-pyrophosphatase activity
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
UDP-2,3-diacylglucosamine hydrolase activity
bis(5'-nucleosyl)-tetraphosphatase activity
dATP pyrophosphohydrolase activity
pyrophosphatase activity
dihydroneopterin monophosphate phosphatase activity
dihydroneopterin triphosphate pyrophosphohydrolase activity
dITP diphosphatase activity
dTTP diphosphatase activity
XTP diphosphatase activity
ATP-dependent 5'-3' DNA helicase activity
phosphocholine hydrolase activity
nucleotide phosphatase
