Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 4
Neurogenin 2 Antibody (PA5-78556) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Neurogenin 2 was performed in DIV9 rat E18 primary hippocampal neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Neurogenin 2 Polyclonal Antibody (Product # PA5 78556) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
产品信息
PA5-78556
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Neurogenin 2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736211
产品详细信息
Positive Control: U87-MG, SK-N-SH, mouse embryonic midbrain
Predicted Reactivity: Rhesus Monkey (98%), Bovine (88%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: atonal homolog 4; bHLHa8; Class A basic helix-loop-helix protein 8; Helix-loop-helix protein mATH-4A; mATH4A; neurogenin 2; Neurogenin-2; neurogenin2; NGN-2; Protein atonal homolog 4
基因别名: Ath4a; ATOH4; BHLHA8; Math4A; NEUROG2; ngn-2; NGN2
UniProt ID: (Human) Q9H2A3, (Mouse) P70447
Entrez Gene ID: (Human) 63973, (Mouse) 11924, (Rat) 295475
transcription, DNA-templated
neuron differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
neuron migration
regulation of transcription, DNA-templated
multicellular organism development
nervous system development
axon guidance
central nervous system neuron development
neurogenesis
cell differentiation
forebrain development
cell fate commitment
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
cell maturation
