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Alomone Labs, LTD
Neuropilin-2 (NRP2) (extracellular) Polyclonal Antibody, FITC
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Neuropilin-2 (NRP2) (extracellular) Antibody (ANR-062-F-50UL) in Flow
Cell surface detection of Neuropilin-2 in live intact human THP-1 acute monocytic leukemia cell line: - (black line) cells. (red) Cells + Rabbit IgG Isotype Control-FITC. (green) Cells + Anti-Neuropilin-2 (NRP2) (extracellular)-FITC Antibody (ANR-062-F), (2.5 µg).
产品信息
ANR-062-F-50UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)REDQGGEWKHGR, corresponding to amino acid residues 747-758 of human neuropilin-2, Extracellular, N-terminus
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); receptor for VEGF165 and semaphorins class3; Vascular endothelial cell growth factor 165 receptor 2
基因别名: 1110048P06Rik; Np-2; NP2; Npn-2; NPN2; NRP2; PRO2714; VEGF165R2
UniProt ID: (Human) O60462, (Mouse) O35375, (Rat) O35276
Entrez Gene ID: (Human) 8828, (Mouse) 18187, (Rat) 81527
angiogenesis
positive regulation of endothelial cell proliferation
cell adhesion
axon guidance
positive regulation of endothelial cell migration
nerve development
vascular endothelial growth factor signaling pathway
vascular endothelial growth factor receptor signaling pathway
axon extension involved in axon guidance
sympathetic ganglion development
sympathetic neuron projection extension
sympathetic neuron projection guidance
semaphorin-plexin signaling pathway involved in neuron projection guidance
neural crest cell migration
neuron migration
multicellular organism development
nervous system development
heart development
facial nerve structural organization
vestibulocochlear nerve structural organization
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
cell differentiation
ventral trunk neural crest cell migration
negative chemotaxis
trigeminal ganglion development
ganglion morphogenesis
semaphorin-plexin signaling pathway
sensory neuron axon guidance
neural crest cell migration involved in autonomic nervous system development
facioacoustic ganglion development
