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产品信息
NOE-100-BIOTIN
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
N-epitope synthetic peptide taken within amino acid region 1-60 on Noelin-1 protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
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生物信息学
蛋白别名: Neuronal olfactomedin-related ER localized protein; Noelin; Noelin 1; Noelin 2; olfactomedin related ER localized protein; Olfactomedin-1; Pancortin; Pancortin 1-4
基因别名: AMY; AW742568; Noe1; Noel; Noel1; OlfA; Olfm1; Pancortin; Pancortin3
UniProt ID: (Mouse) O88998
Entrez Gene ID: (Mouse) 56177
