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Specificity: a 125 kD nucleoplasmic protein (AND-1, acidic nucleoplasmic DNA-binding protein) in Xenopus. Immunolocalization studies showed a dispersed, finely granular distribution pattern throughout the nucleoplasm.
The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CRM1/XPO1 protein; exportin 1 (CRM1 homolog)
基因别名: crm1; exportin-1; XELAEV_18028477mg; Xpo; xpo1
Entrez Gene ID: (Xenopus) 399087