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This target displays homology in the following species: Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2',5'-oligoadenylate synthetase-like 9; 2'-5'-oligoadenylate synthase-like protein 1; 2,5-oligoadenylate synthetase-like 9
基因别名: 7530414C13Rik; Oasl1; oasl9
UniProt ID: (Mouse) Q8VI94
Entrez Gene ID: (Mouse) 231655