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Immunogen sequence: QGKDTKASDN ERKVMDEANL EFLNNGEHFV PSAGTDSKTC NLDMQDNAAA
SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. The molecular mass of SLCO1B3 is highly dependent on the glycosylation modification (deglycosylated form of 65 kDa, fully-glycosylated form of 120 kDa).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; LST-2; OATP-8; OATP1B3; Organic anion transporter 8; organic anion transporter LST-3c; Organic anion-transporting polypeptide 8; solute carrier family 21 (organic anion transporter), member 8; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family, member 1B3
基因别名: HBLRR; LST-2; LST-3TM13; LST2; LST3; OATP-8; OATP1B3; OATP8; SLC21A8; SLCO1B3
UniProt ID: (Human) Q9NPD5
Entrez Gene ID: (Human) 28234