Abnova

OLFM3 Monoclonal Antibody (1F11)

产品信息

H00118427-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

1F11

抗原

OLFM3 (NP_477518, 108 a.a. approximately 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

产品详细信息

Immunogen sequence: FRQIEDDRKT LMTKHFQELK EKMDELLPLI PVLEQYKTDA KLITQFKEEI RNLSAVLTGI QEEIGAYDYE ELHQRVLSLE TRLRDCMKKL TCGKLMKIT

靶标信息

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

仅用于科研。不用于诊断过程。未经明确授权不得转售。