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OLIG2 Antibody (PA5-117535) in WB
Western Blot analysis of OLIG2 using OLIG2 Polyclonal Antibody (Product # PA5-117535) at 2 µg/mL. Positive WB detected in Recombinant protein. Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 44 kDa. Observed band size: 44 kDa
产品信息
PA5-117535
产品规格
种属反应
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Zebrafish Oligodendrocyte lineage transcription factor 2 protein (150-273aa)
偶联物
Unconjugated
形式
Liquid
浓度
2.5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2902164
产品详细信息
This antibody has been tested in direct-ELISA
靶标信息
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); olig-2; Oligo2 antibody; Oligodendrocyte specific bHLH transcription factor 2; Protein kinase C-binding protein 2 (PRKCBP2)
基因别名: wu:fc64g09
Entrez Gene ID: (Zebrafish) 325288
neuron migration
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
neuroblast fate determination
glial cell fate determination
oligodendrocyte development
ventral spinal cord interneuron differentiation
spinal cord motor neuron cell fate specification
spinal cord motor neuron differentiation
abducens nucleus development
facial nucleus development
oligodendrocyte cell fate specification
neuron differentiation
myelination
neuron development
oligodendrocyte differentiation
positive regulation of neurogenesis
dopaminergic neuron differentiation
