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This antibody has been tested in direct-ELISA
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); olig-2; Oligo2 antibody; Oligodendrocyte specific bHLH transcription factor 2; Protein kinase C-binding protein 2 (PRKCBP2)
基因别名: wu:fc64g09
Entrez Gene ID: (Zebrafish) 325288