Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
OMA1 Antibody (PA5-106421) in ICC/IF
Immunofluorescent analysis of OMA1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and OMA1 polyclonal antibody (Product # PA5-106421) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106421
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human OMA1(Accession Q96E52), corresponding to amino acid residues K405-Q455.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854093
产品详细信息
Antibody detects endogenous levels of total OMA1.
靶标信息
OMA1 (Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family. It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants, and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Metalloendopeptidase OMA1, mitochondrial; metalloprotease related protein 1; Metalloprotease-related protein 1; MPRP-1; OMA1 homolog, zinc metallopeptidase; OMA1 zinc metallopeptidase homolog; overlapping activity with M-AAA protease; Overlapping with the m-AAA protease 1 homolog; zinc metallopeptidase homolog; zinc metallopeptidase OMA1
基因别名: 2010001O09Rik; DAB1; MPRP-1; MPRP1; OMA1; peptidase; RGD1304821; YKR087C; ZMPOMA1
UniProt ID: (Human) Q96E52, (Mouse) Q9D8H7, (Rat) D3ZS74
Entrez Gene ID: (Human) 115209, (Mouse) 67013, (Rat) 298282
diet induced thermogenesis
glucose metabolic process
misfolded or incompletely synthesized protein catabolic process
lipid metabolic process
response to stress
negative regulation of mitochondrial fusion
mitochondrial protein processing
cristae formation
energy homeostasis
proteolysis
mitochondrion organization
