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Sequence of this protein is as follows: MALSWVLTVL SLLPLLEAQI PLCANLVPVP ITNATLDQIT GKWFYIASAF RNEEYNKSVQ EIQATFFYFT PNKTEDTIFL REYQTRQDQC IYNTTYLNVQ RENGTISRYV GGQEHFAHLL ILRDTKTYML AFDVNDEKNW GLSVYADKPE TTKEQLGEFY EALDCLRIPK SDVVYTDWKK DKCEPLEKQH EKERKQEEGE S
ORM1 is an acute phase plasma protein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation. ORM1 is a major acute phase reactant, both in human and in rat. In human plasma, ORM1 (44 kDa) is found at levels of 0.5-1.4 mg/mL. Its concentration in blood plasma is elevated during acute inflammation, such as trauma, malignancies, myocardial infarction, rheumatoid arthritis, bacterial infections, after major surgery, in cases of chronic pain etc, and can be used for the diagnosis of inflammatory conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AGP 1; Alpha-1-acid glycoprotein 1; alpha-1-acid glycoprotein-2; bM340H1.2 (orosomucoid 1); epididymis secretory sperm binding protein Li 153w; OMD 1; Orosomucoid-1
基因别名: Agp-1; Agp-2; AGP-A; AGP1; HEL-S-153w; ORM; Orm-1; ORM1
UniProt ID: (Human) P02763, (Mouse) Q60590
Entrez Gene ID: (Human) 5004, (Mouse) 18405