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产品信息
BS-0427R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human P311, amino acids 25-68.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: high-altitude regulated protein; Neuronal protein 3.1; neuronal regeneration related protein homolog; Neuronal regeneration-related protein; Protein p311
基因别名: AI325076; C5orf13; D0H4S114; D4S114; Harp; NREP; P311; PRO1873; PTZ17; SEZ17
UniProt ID: (Human) Q16612, (Mouse) Q07475
Entrez Gene ID: (Human) 9315, (Rat) 338475, (Mouse) 27528
