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产品信息
61567
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
This antibody was raised against a peptide within human PAF1.
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.5, with 30% glycerol
内含物
0.035% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2793679
靶标信息
This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPAF1; Paf1, RNA polymerase II associated factor, homolog; Pancreatic differentiation protein 2; RNA polymerase II-associated factor 1 homolog
基因别名: F23149_1; PAF1; PD2
UniProt ID: (Human) Q8N7H5
Entrez Gene ID: (Human) 54623
negative regulation of transcription from RNA polymerase II promoter
endodermal cell fate commitment
transcription elongation from RNA polymerase II promoter
mRNA polyadenylation
histone monoubiquitination
Wnt signaling pathway
nucleosome positioning
stem cell population maintenance
positive regulation of histone methylation
positive regulation of mRNA 3'-end processing
positive regulation of transcription elongation from RNA polymerase II promoter
histone H2B ubiquitination
protein localization to nucleus
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
