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Immunogen sequence: MSQGDSNPA AIPHAAEDIQ GDDRWMSQHN RFVLDCKDKE PDVLFVGDSM VQLMQQYEIW RELFSPLHAL NFGIGGDTTR HVLWRLKNGE LENIKPKVIV VWVGTNNHEN TAEEVAGGIE AIVQLINTRQ PQAKIIVLGL LPRGEKPNPL RQKNAKVNQL LKVSLPKLAN VQLLDTDGGF VHSDGAISCH DMFDFLHLTG GGYAKICKPL HELIMQLLEE TPEEKQTTIA (1-229 aa encoded by BC000398)
Platelet-activating factor (PAF) is a biologically active phospholipid with diverse biologic effects. PAF is degraded to inactive products by hydrolysis of the acetyl group at the sn-2 position to produce the biologically inactive products LYSO-PAF and acetate. This reaction is catalyzed by PAF acetylhydrolase (PAFAH). The various monomeric and multimeric forms of the enzyme are composed of alpha, beta, and gamma PAFAH subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymis secretory protein Li 303; intracellular platelet-activating factor acetylhydrolase alpha 2 subunit; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH alpha 2; PAF-AH subunit beta; PAF-AH1b alpha 2 subunit; PAFAH subunit beta; pl; platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa); Platelet-activating factor acetylhydrolase alpha 2 subunit; platelet-activating factor acetylhydrolase alpha 2 subunit (PAF-AH alpha 2); Platelet-activating factor acetylhydrolase IB subunit alpha2; platelet-activating factor acetylhydrolase IB subunit beta; platelet-activating factor acetylhydrolase, isoform 1b, alpha2 subunit; platelet-activating factor acetylhydrolase, isoform 1b, subunit 2; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 2; platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa)
基因别名: AI747451; AU021353; HEL-S-303; mus[b]; PAFAH1B2; PAFAHB
UniProt ID: (Human) Q29459, (Rat) O35264, (Mouse) Q61206
Entrez Gene ID: (Human) 5049, (Rat) 64189, (Mouse) 18475
分子生物学功能:
protein modifying enzyme