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Invitrogen
PAX3 Monoclonal Antibody (GT1210)
高级验证
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
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PAX3 Antibody (MA5-31583) in IHC (P)
Immunohistochemistry (Paraffin) analysis of PAX3 was performed in paraffin-embedded human esophageal carcinoma tissue using PAX3 Monoclonal Antibody (GT1210) (Product # MA5-31583) at a dilution of 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
MA5-31583
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
GT1210
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human PAX3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7, with 20% glycerol
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787210
产品详细信息
Keep as concentrated solution.
Positive Control: U87-MG, U87-MG nuclear extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Pax 3 (Paired Box 3) is a transcription factor that is involved in development of the peripheral nervous system, melanocytes, some vascular smooth muscle, and a number of other derivatives. It regulates neurogenesis in pre-migratory neural crest cells from the dorsal neural tube, and in myogenic progenitors in the presomitic mesoderm and the hypaxial somites. Alternative splicing results in isoforms having different C-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeodomain protein PAX3; HuP2; MGC120381; MGC120382; MGC120383; MGC120384; MGC134778; paired box gene 3; paired box homeotic gene 3; Paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2; PAX3/FKHR fusion
基因别名: CDHS; HUP2; Pax-3; PAX3; Sp; splotch; WS1; WS3
UniProt ID: (Human) P23760, (Mouse) P24610
Entrez Gene ID: (Human) 5077, (Rat) 114502, (Mouse) 18505
transcription from RNA polymerase II promoter
apoptotic process
nervous system development
muscle organ development
sensory perception of sound
organ morphogenesis
neural crest formation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
neural tube closure
heart development
cell proliferation
positive regulation of cell proliferation
regulation of somitogenesis
cell migration
spinal cord association neuron differentiation
neural tube development
gliogenesis
developmental pigmentation
neuron fate commitment
skeletal muscle organ development
mammary gland specification
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
skeletal muscle cell differentiation
cardiac muscle cell differentiation
