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产品信息
PA1-31145
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide (Human) against a common sequence near the 250-325 amino acids downstream from the N terminal region of PDE10A.
偶联物
形式
Liquid
浓度
0.70 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris glycine, pH 7.4-7.9, with 30% glycerol, 0.5% BSA
内含物
0.02% thimerosal, 0.02% Sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2162587
产品详细信息
Recommended positive controls: For western blot - Rat brain and pancreas.
靶标信息
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; PDE10A2 brain-specific isoform; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7); testis-specific phosphodiesterase PDE10A2
基因别名: ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19; Pde10a3
UniProt ID: (Human) Q9Y233, (Mouse) Q8CA95, (Rat) Q9QYJ6
Entrez Gene ID: (Human) 10846, (Mouse) 23984, (Rat) 63885
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
drug binding
cAMP binding
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity
nucleotide binding
catalytic activity
cyclic-nucleotide phosphodiesterase activity
phosphoric diester hydrolase activity
hydrolase activity
phosphodiesterase
